Lentiviral human HTR2B sgRNA gene knockout kit

Human HTR2B

Gene symbol: HTR2B
Synonyms: 5-HT(2B) 5-HT-2B 5-HT2B
Species: HUMAN
Gene ID: 3357
Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000867:4:3 NM_001320758:4:3