Lentiviral human HTR2A sgRNA gene knockout kit

Human HTR2A

Gene symbol: HTR2A
Synonyms: 5-HT2A HTR2
Species: HUMAN
Gene ID: 3356
Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000621:4:3 NM_001165947:3:3