Lentiviral human HLA-DQA2 sgRNA gene knockout kit

Human HLA-DQA2

Gene symbol: HLA-DQA2
Synonyms: DC-alpha DX-ALPHA HLA-DCA HLA-DXA HLADQA2
Species: HUMAN
Gene ID: 3118
Summary: This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_020056:2:2