Lentiviral human HADHB sgRNA gene knockout kit

Human HADHB

Gene symbol: HADHB
Synonyms: ECHB MSTP029 MTPB TP-BETA
Species: HUMAN
Gene ID: 3032
Summary: This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000183:8:7 NM_001281512:7:6 NM_001281513:9:6