Lentiviral human FLNC sgRNA gene knockout kit

Human FLNC

Gene symbol: FLNC
Synonyms: ABP-280 ABP280A ABPA ABPL CMH26 FLN2 MFM5 MPD4 RCM5
Species: HUMAN
Gene ID: 2318
Summary: This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001458:8:8 NM_001127487:8:8