Lentiviral human EPHB3 sgRNA gene knockout kit

Human EPHB3

Gene symbol: EPHB3
Synonyms: EK2 ETK2 HEK2 TYRO6
Species: HUMAN
Gene ID: 2049
Summary: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004443:3:3