Lentiviral human EARS2 sgRNA gene knockout kit

Human EARS2

Gene symbol: EARS2
Synonyms: COXPD12 gluRS MSE1 mtGlnRS
Species: HUMAN
Gene ID: 124454
Summary: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001083614:1:1 NM_001308211:1:1