Lentiviral human E4F1 sgRNA gene knockout kit

Human E4F1

Gene symbol: E4F1
Synonyms: E4F
Species: HUMAN
Gene ID: 1877
Summary: The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004424:5:5