Lentiviral human COLEC11 sgRNA gene knockout kit

Lentiviral human COLEC11 sgRNA gene knockout kit

Catalog Number:
CGKK545390FEN
Mfr. No.:
HKO-611920
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human COLEC11
          About Target
          Gene symbol: COLEC11
          Synonyms: 3MC2 CL-K1-I CL-K1-II CL-K1-IIa CL-K1-IIb CLK1
          Species: HUMAN
          Gene ID: 78989
          Summary: This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_024027:7:6
      • Properties
        • * For Research Use Only.

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