Lentiviral human BRD2 sgRNA gene knockout kit

Human BRD2

Gene symbol: BRD2
Synonyms: BRD2-IT1 D6S113E FSH FSRG1 NAT O27.1.1 RING3 RNF3
Species: HUMAN
Gene ID: 6046
Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_005104:7:6 NM_001199455:6:6 NM_001199456:6:5 NM_001291986:8:4 NM_001113182:7:6