Lentiviral human ALDH5A1 sgRNA gene knockout kit

Human ALDH5A1

Gene symbol: ALDH5A1
Synonyms: SSADH SSDH
Species: HUMAN
Gene ID: 7915
Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_170740:4:4 NM_001080:4:4 NM_001368954:4:4