Lentiviral human ALDH3A1 sgRNA gene knockout kit

Human ALDH3A1

Gene symbol: ALDH3A1
Synonyms: ALDH3 ALDHIII
Species: HUMAN
Gene ID: 218
Summary: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001135168:4:4 NM_000691:5:4 NM_001135167:5:4 NM_001330150:4:3