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Overview
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Background
Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).
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- Properties
- Applications
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Overview
LEF1 Rabbit mAb
LEF1 Rabbit mAb
Catalog Number:
A001550071RED
Mfr. No.:
RDSA66669
Price:
$470
Size:
100μL
Quantity:
Add to Cart: