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Overview
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KSOM is a potassium simplex optimized medium for in vitro culture of mouse oocytes. Simplex Optimized Medium (SOM) is taken and modified with an increased potassium concentration to make KSOM. KSOM can not only overcome the two-cell block problem that occurs in SOM, it also has the benefit of a higher yield of blastocysts, stimulates a higher rate of cell division of the trophoblast cells, and supports a greater rate of development from zygote to blastocyst of an outbred strain of mouse when compared with other culture media.
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Overview