Kisspeptin 234

Kisspeptin 234

Catalog Number:
P004516737LIF
Mfr. No.:
PEPTIDE-KR-010
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  • Size:
    1mg
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      • Overview

        • Kisspeptin receptor antagonist.
          Kisspeptin 234 is an analogue of kisspeptin 10 which acts as a kisspeptin receptor antagonist. Of a series, kisspeptin 234 most potently inhibited kisspeptin 10 stimulation of inositol phosphate release in Chinese hamster ovarian cells stably expressing the human GPR54 with an IC50 of 7 nM. Intracerebroventricular administration of kisspeptin 234 causes delayed vaginal opening in rats (an indicator of puberty) and prevents an increase in circulating luteinising hormone concentration when co-administrated with kisspeptin 10.

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      • Properties
        • Categories
          Kisspeptin Receptor Modulators
          Alternative Name
          Peptide 234, p234, K234
          Molecular Formula
          C63H78N18O13
          Molecular Weight
          1295.42
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: Ac-(D)Ala-Asn-Trp-Asn-Gly-Phe-Gly-(D)Trp-Arg-Phe-NH2,Ac-aNWNGFGwRF-NH2
          Modification: N-terminal acetyl, C-terminal amide; Ala-1 is D-Ala and Trp-8 is D-Trp
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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