Name: Kijanimicin
Price: 416.00 USD

- Overview
  - Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor active. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.
    
    Kijanimicin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
    
    Please contact us at for specific academic pricing.
- Properties
  - CAS Number
    
    78798-08-0
    
    Molecular Formula
    
    C67H100N2O24
    
    Molecular Weight
    
    1317.5
    
    Appearance
    
    White solid
    
    Storage
    
    -20°C
    
    * For research use only