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ITCH Rabbit mAb

ITCH Rabbit mAb

Catalog Number:

A001550825RED

Mfr. No.:

RDSA67422

Price:

$470

Size:

100μL

Quantity:

Add to Cart:

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  Involved in the negative regulation of MAVS-dependent cellular antiviral responses. Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteosomal degradation. Involved in the regulation of apoptosis and reactive oxygen species levels through the ubiquitination and proteosomal degradation of TXNIP. Mediates the antiapoptotic activity of epidermal growth factor through the ubiquitination and proteosomal degradation of p15 BID.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthesized peptide derived from human ITCH
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Antigen
  
  ADMFD;AIF4;AIP4;Atrophin 1 interacting protein 4;Itchy homolog E3 ubiquitin protein ligase;NAPP1;NFE2 associated polypeptide 1;Ubiquitin protein ligase ITCH (UniProt:Q96J02)
  
  * This product is for Research Use Only.

Applications

Application

WB

Application	Dilutions
WB	1:500-1:2000

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