Name: IRBP (651-670) (human)
Price: Inquiry

- Overview
  - Residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP).
    IRBP (651-670) (human), sometimes referred to as hIRBP651-670 or human IRBP651-670, is amino acid residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP), which has been identified as a new uveitogenic epitope. IRBP (651-670) (human) is uveitogenic for mice of the H-2b haplotype and elicits experimental autoimmune uveitis (EAU) with a higher severity and incidence in C57BL/6 mice than the previously characterized IRBP (1-20) (human) epitope. Co-immunization with IRBP (1-20) (human) and IRBP (651-670) human is additive but not synergistic. IRBP (651-670) (human) appears to be an epitope naturally processed from a conserved region of native IRBP.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    hIRBP651-670, human IRBP651-670
    
    Molecular Formula
    
    C91H151N25O32
    
    Molecular Weight
    
    2107.35
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in water
    
    Other Properties
    
    Sequence: H-Leu-Ala-Gln-Gly-Ala-Tyr-Arg-Thr-Ala-Val-Asp-Leu-Glu-Ser-Leu-Ala-Ser-Gln-Leu-Thr-OH,LAQGAYRTAVDLESLASQLT
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

IRBP (651-670) (human)

IRBP (651-670) (human)

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