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IRL 1620

IRL 1620

Catalog Number:
P004516850LIF
Mfr. No.:
PEPTIDE-ER-020
Price:
$298
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Highly selective endothelin B receptor agonist.
          IRL 1620 is an N-succinylated endothelin-1 analogue which acts as a highly selective ETB endothelin receptor agonist, with Ki values of 0.016 and 1900 nM at ETB and ETA receptors respectively. IRL 1620 can also discriminate between two subpopulations of ETB receptors, and in vivo IRL 1620 can significantly reduce neurological and motor deficit as well as infarct volume in a pediatric rat model of cerebral ischemia.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          Suc-[Glu9,Ala11,15]-endothelin-1(8-21)
          Molecular Formula
          C86H117N17O27
          Molecular Weight
          1820
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 0.70 mg/ml in water
          Other Properties
          Sequence: Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH,Suc-DEEAVYFAHLDIIW
          Modification: Asp-1 is succinylated
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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