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Overview
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Introducing highly-defined, consistent and reliable human muscle cells for research, disease modelling and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes have been reprogrammed from human induced pluripotent stem cells (iPSCs) using our precise reprogramming technology: opti-ox™¹.
The technology allows for human pluripotent stem cells, within days, to convert into skeletal myocytes, providing a high-quality, easy to use, cellular model.
Skeletal myocytes demonstrate robust expression of components of the contractile apparatus and form striated, multinucleated, myocytes by Day 10 post revival, that contract in response to acetylcholine.
Unprecedented batch-to-batch consistency allows for their use in demanding screening applications where small changes need to be detected against background noise.
■ Consistency
Batch to batch reproducibility and homogeneity create a stable human model for the study of muscle, neuromuscular, and associated metabolic disorders.
■ Speed
Form striated, multinucleated, myocytes by Day 10 post revival, that contract in response to acetylcholine.
■ Scalability
Industrial scale quantities at a price point that allows the cells to be used from research to screening scale.
■ Ease of Use
Cells arrive programmed to rapidly mature upon revival. One medium required in a two-step protocol.Please contact us at for specific academic pricing.
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- Properties
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Overview