Name: IF1-Intrinsic Factor
Price: Inquiry

- Overview
  - What is pernicious anaemia?
    Intrinsic Factor is primarily used in the diagnosis of pernicious anaemia, a condition caused by a vitamin B12 deficiency. Prevalence in the general population varies from around 3% - 5%, and increases dramatically to 5% - 20% among people older than 65 years.
    The role of Intrinsic Factor in diagnosis
    Intrinsic Factor has a high affinity and specificity to vitamin B12, which makes it ideal for use in immunoassays. Most commercial assays utilise a competitive binding technique generating a chemiluminescent signal. Commercial assays can usually detect to a level of ~50 pg/ml vitamin B12.
    Why choose BBI for your supply?
    BBI is the only commercial manufacturer of high purity Intrinsic Factor. BBI’s porcine Intrinsic Factor is manufactured in the UK, under a quality system compliant with ISO 13485:2016. Using our expertise in raw material sourcing and protein purification we achieve exceptional purity, making BBI the supplier of choice.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Porcine stomach pyloric section
    
    Formulation
    
    IF Content: > 1.00 x106 ng/ml
    (IF functional ELISA)
    Purity: > 95%
    (Size exclusion
    chromatography
    SDS-Page: One major band at 55kDa
    Protein concentration: 0.4 – 0.6 mg protein/ml
    (Determined by A280 /1.4)
    
    Storage
    
    Store between -25°C and -10°C.