Human SMO-Strep full length protein-synthetic nanodisc

Human SMO-Strep full length protein-synthetic nanodisc

Catalog Number:
P001561698DIM
Mfr. No.:
FLP120466
Price:
$911
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      • Overview
        • Target: SMO
          Tag: C-Flag&Strep Tag
          Synonyms: CRJS, FZD11, Gx, PHLS, SMOH
          Protein Families: ES Cell Differentiation/IPS , Transmembrane, Stem cell relevant signalingDSL/Notch pathway, Druggable Genome
          Protein Pathways: GPCRDB Other, Hedgehog Netpath 10, Hedgehog Netpath 10, Apoptosis, Cancer, Notch

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          Background

          The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length SMO-Strep protein has a MW of 86.4 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q99835

          * For research use only.

    Documents

    Datasheet