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Overview
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Target Information
Target NameSignal Peptide - Cub And Egf-Like Domain-Containing Protein 1Database LinksSCUB1_HUMAN ; Reactome: R-HSA-1474228 ; Gene ID: 80274About TargetTissue Specificity: Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
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Overview