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Overview
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Target Information
Target NameSecreted Frizzled-Related Protein 2; Frp-2; Sfrp-2; Secreted Apoptosis-Related Protein 1; Sarp-1Database LinksSFRP2_HUMAN ; Reactome: R-HSA-201681 ; Gene ID: 6423About TargetTissue Specificity: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
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