Human Prothrombin Complex

Human Prothrombin Complex

Catalog Number:
P001413754ABE
Mfr. No.:
Abe32-4521
Price:
  • Size:
    50 IU
    Quantity:
    Add to Cart:
      • Overview
        • Prothrombin complex is a double virus-inactivated concentrate, containing equal concentrations of Factors II, VIII, IX, X and Heparin. Prothrombin Complex Concentrate (PCC) is a combination of several blood clotting factors II, VII, IX and X. PCC is used in the treatment of the congenital bleeding disorders associated with Factors II, VII, IX, and X deficiencies. PCC reverses the effect of warfarin (a coumarin anti-coagulant) and is used in cases of significant bleeding in patients with a coagulopathy, for example, gastrointestinal haemorrhage or intracranial haemorrhage. The PCC is also extensively used in treating acquired coagulation abnormalities secondary to vitamin K deficiency, warfarin ingestion, and various types of liver disease. Hepatitis, anaphylaxis and thrombosis have been reported as complications of prothrombin complex concentrates administration.

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      • Properties
        • Protein Name
          PCC, Prothrombin Complex.
          Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Lyophilized Powder from 0.1M sodium chloride and 10mM sodium citrate buffer.
          Storage
          Lyophilized Prothrombin-Complex although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prothrombin-Complex should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized Prothrombin Complex in sterile 18MΩ-cm H2O.

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