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Overview
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This PLSCR2 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NamePhospholipid Scramblase 2; Pl Scramblase 2; Ca(2+-Dependent Phospholipid Scramblase 2Database LinksPLS2_HUMAN ; Gene ID: 57047About TargetTissue Specificity: Expression of isoform 1 seems restricted to testis.
Function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.
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