Human PLSCR1 (Phospholipid Scramblase 1) CLIA Kit

Phospholipid Scramblase 1; Pl Scramblase 1; Ca(2+-Dependent Phospholipid Scramblase 1; Erythrocyte Phospholipid Scramblase; Mmtra1b

PLS1_HUMAN ; Gene ID: 5359

Tissue Specificity: Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.

Function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.