Human OR2S2-Strep full length protein-synthetic nanodisc

Human OR2S2-Strep full length protein-synthetic nanodisc

Catalog Number:
P001561684DIM
Mfr. No.:
FLP120413
Price:
$911
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      • Overview

        • Target: OR2S2
          Tag: C-Flag&Strep Tag
          Synonyms: OR37A, OST715
          Protein Families: Transmembrane, Druggable Genome
          Protein Pathways: GPCRDB Class A Rhodopsin-like

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          Background

          Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length OR2S2-Strep protein has a MW of 35.2 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q9NQN1

          * For research use only.

    MSDS

    Documents

    Datasheet

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