Human Methacryloyl Placenta (hPCMA)

hPCMA - Human Methacryloyl Placenta is a bioactive placentabased platform that provides physiologically relevant microenvironments for cells cultured in vitro. The precursor solution is easily prepared by reconstituting hPCMA lyophilizate in an aqueous solution with a photoinitiator. Afterwards, it can be cured upon light exposure to form a hydrogel with tuneable mechanical properties. hPCMA hydrogels provide great control over gelation time and matrix stiffness, enabling researchers to create the cell culture environment that better fits their needs.

hPCMA, a photopolymerizable hydrogel, is composed of several extracellular matrix (ECM) proteins, including multiple collagen types (e.g., I, III, IV, and VI), as well as fibrinogen, laminin, fibrillin, and fibronectin. These bioactive components are well recognized as key constituents of the extracellular matrix, playing crucial roles in supporting cell adhesion, growth, and proliferation.

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