Name: Human Macrophage Inflammatory Protein-3 beta (CCL19)
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- Overview
  - Predicted MW: Monomer, 8.8 kDa (77 aa). Macrophage inflammatory protein-3 beta (MIP-3 beta ), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3 beta signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3 beta also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. Human MIP-3 beta shows activity on mouse cells.
    
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- Properties
  - Protein Name
    
    C-C motif chemokine 19, Beta-chemokine exodus-3, Epstein-Barr virus-induced molecule 1 ligand chemokine, Macrophage inflammatory protein 3 beta
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Bioactive protein. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    Q99731
    
    Gene ID
    
    6363
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Macrophage Inflammatory Protein-3 beta (CCL19)

Human Macrophage Inflammatory Protein-3 beta (CCL19)

More Information

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