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Target Information
Target NameProtein-Lysine 6-Oxidase; Lysyl Oxidase Cleaved Into - Protein-Lysine 6-Oxidase - Long Form - Protein-Lysine 6-Oxidase - Short FormDatabase LinksLYOX_HUMAN ; Reactome: R-HSA-1566948 ; Gene ID: 4015About TargetTissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Function: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture.
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