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Overview
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Target Information
Target NameUbiquitin-Like Protein Isg15; Interferon-Induced 15 Kda Protein; Interferon-Induced 17 Kda Protein; Ip17; Ubiquitin Cross-Reactive Protein; HucrpDatabase LinksISG15_HUMAN ; Reactome: R-HSA-1169408 ; Gene ID: 9636About TargetTissue Specificity: Detected in lymphoid cells, striated and smooth muscle, several epithelia and neurons. Expressed in neutrophils, monocytes and lymphocytes. Enhanced expression seen in pancreatic adenocarcinoma, endometrial cancer, and bladder cancer, as compared to non-cancerous tissue. In bladder cancer, the increase in expression exhibits a striking positive correlation with more advanced stages of the disease.
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Overview