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Overview
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Predicted MW: Monomer, 14.9 kDa (131 aa). Interleukin 32 alpha (IL-32 alpha) is one of six known splice variants of the IL-32 gene. IL-32 alpha induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), and macrophage inflammatory protein 2 (MIP-2). IL-32 alpha expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.
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Overview