Human IL-23 ELISA Kit

Interleukin-23 Subunit Alpha; Il-23 Subunit Alpha; Il-23-A; Interleukin-23 Subunit P19; Il-23p19

Uniprot ID: LKHA4_HUMAN ; Reactome: R-HSA-6785807 ; Gene ID: 51561 ; Gene Symbol: IL23A

Function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.