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Overview
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This IL18 ELISA kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
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Target Information
Target NameInterleukin-18; Il-18; Iboctadekin; Interferon Gamma-Inducing Factor; Ifn-Gamma-Inducing Factor; Interleukin-1 Gamma; Il-1 GammaDatabase LinksUniprot ID: HLAA_HUMAN ; Reactome: R-HSA-448706 ; Gene ID: 3606 ; Gene Symbol: IL18About TargetFunction: A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable).
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