Human IL-18 ELISA Kit

Interleukin-18; Il-18; Iboctadekin; Interferon Gamma-Inducing Factor; Ifn-Gamma-Inducing Factor; Interleukin-1 Gamma; Il-1 Gamma

Uniprot ID: HLAA_HUMAN ; Reactome: R-HSA-448706 ; Gene ID: 3606 ; Gene Symbol: IL18

Function: A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable).