Human IL-1 beta ELISA Kit

Interleukin-1 Beta; Il-1 Beta; Catabolin

Uniprot ID: MMP11_HUMAN ; Reactome: R-HSA-448706 ; Gene ID: 3553 ; Gene Symbol: IL1B

Function: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.