Name: Human Heparin Binding EGF-like Growth Factor (AF)
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 9.9 kDa (87 aa). Heparin-binding EGF-like growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) family and is expressed by monocytes and macrophages. HB-EGF is the predominant growth factor involved in epithelialization during wound healing. HB-EGF signals through the receptor tyrosine kinase ErbB2 to maintain adult heart homeostasis, and promotes cardiac valve development through binding in high affinity to the epidermal growth factor receptor (EGFR). HB-EGF binds the the ErbB4 receptor tyrosine kinase to mediate implantation of the human blastocyst. HB-EGF also functions as a potent mitogen for fibroblasts and smooth muscle cells.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    DTR, DTS, HEGFL, Diphtheria toxin receptor
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by3T3 cell proliferation at = 1.0 x 10^6 units/mg . Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    Q99075
    
    Gene ID
    
    1839
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Heparin Binding EGF-like Growth Factor (AF)

Human Heparin Binding EGF-like Growth Factor (AF)

More Information

We Also Recommend

FST His Recombinant Protein

Human Interferon-alpha 2a

Human Interferon-alpha 2b