Name: Human Interferon-alpha 2b
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 19.4 kDa (166 aa). Interferon-alpha 2b (IFN-alpha 2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-alpha 2b. IFN-alpha proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-alpha 2b variant differs from IFN-alpha 2a by one amino acid.
    
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- Properties
  - Protein Name
    
    IFNA2A, IFNA2B, IFNA2C, Interferon alpha-A
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Viral CPE assay using EMC virus on A549 cells , at: >= 2.0 x 10^8 units/mg. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    P01563
    
    Gene ID
    
    3440
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Interferon-alpha 2b

Human Interferon-alpha 2b

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