Name: Human Growth and Differentiation Factor-5
Price: Inquiry

- Overview
  - Predicted MW: Dimer, 13.7/27.4 kDa (121/242 aa). Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-beta ) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is expressed in the central nervous system and promotes the survival of dopaminergic neurons in animal models of Parkinsons disease. GDF-5 is also important during chondrogenesis and chondrocyte differentiation.
    
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- Properties
  - Protein Name
    
    BMP14, CDMP1, Bone morphogenetic protein 14, Cartilage-derived morphogenetic protein 1, Lipopolysaccharide-associated protein 4, Radotermin
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Alkaline phosphatase activity in ATDC5 cells at
    
    More Information
    
    UniProt
    
    P43026
    
    Gene ID
    
    8200
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Growth and Differentiation Factor-5

Human Growth and Differentiation Factor-5

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