Name: Human Follistatin
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 31.7 kDa (289 aa). Follistatin is an autocrine, activin-binding protein that is ubiquitously expressed with highest expression levels being in the ovary and skin. Follistatin negatively regulates the signaling of transforming growth factor beta (TGF-beta ) family members, such as activin, bone morphogenetic proteins (BMPs), myostatin, growth differentiation factor 11 (GDF-11), and TGF-beta 1. Follistatin functions as an antagonist by binding TGF-beta family members to block interaction with their signaling receptors. Follistatin also inhibits the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Activin-binding protein, FSH-suppressing protein (FSP), FS
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Neutralization of Human Activin A induced cytotoxicity of MPC-11 cells at
    
    More Information
    
    UniProt
    
    P19883
    
    Gene ID
    
    10468
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Follistatin

Human Follistatin

More Information

We Also Recommend

Human Fractalkine (CX3CL1)

Human Galectin-1

Mouse Follistatin