Name: Mouse Follistatin
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 31.6 kDa (289 aa). Follistatin is an autocrine, activin-binding protein that is ubiquitously expressed with highest expression levels being in the ovary and skin. Follistatin negatively regulates the signaling of transforming growth factor beta (TGF-beta ) family members, such as activin, bone morphogenetic proteins (BMPs), myostatin, growth differentiation factor 11 (GDF-11), and TGF-beta 1. Follistatin functions as an antagonist by binding TGF-beta family members to block interaction with their signaling receptors. Follistatin also inhibits the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary.
    
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- Properties
  - Protein Name
    
    Activin-binding protein, FSH-suppressing protein (FSP), FS
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 90%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.5 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P47931
    
    Gene ID
    
    14313
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

Mouse Follistatin

Mouse Follistatin

More Information

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