Name: Human Fibroblast Growth Factor-8
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 22.5 kDa (194 aa). Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.
    
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- Properties
  - Protein Name
    
    Androgen-induced growth factor, Heparin-binding growth factor 8, AIGF
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 5 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by 3T3 cell proliferationat <=150 ng/mL; >= 6.7 x 10^3 units/mg (typical ED50 is < 20 ng/mL). Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    P55075
    
    Gene ID
    
    2253
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Fibroblast Growth Factor-8

Human Fibroblast Growth Factor-8

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