Mouse Fibroblast Growth Factor-8 (AF)

Mouse Fibroblast Growth Factor-8 (AF)

Catalog Number:
P001412044ABE
Mfr. No.:
Abe32-12055
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      • Overview
        • Predicted MW: Monomer, 22.5 kDa (194 aa). Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.

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      • Properties
        • Protein Name
          Androgen-induced growth factor, Heparin-binding growth factor 8, AIGF
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 5 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
          Activity
          Biological Activity was determined by 3T3 cell proliferationat <=150 ng/mL; >= 6.7 x 10^3 units/mg (typical ED50 is < 20 ng/mL). Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

          More Information

          UniProt
          Gene ID
          2253

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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