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Overview
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This FGF2 ELISA kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
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Target Information
Target NameFibroblast Growth Factor 2; Fgf-2; Basic Fibroblast Growth Factor; Bfgf; Heparin-Binding Growth Factor 2; Hbgf-2Database LinksUniprot ID: CSF2_HUMAN ; Reactome: R-HSA-109704 ; Gene ID: 2247 ; Gene Symbol: FGF2About TargetFunction: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.
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Overview