Name: Human CD8 [C8/144B] Monoclonal Antibody
Price: 200.00 USD

Overview
- Sensitivity: Endogenous
  Target name: Human CD8 [C8/144B] monoclonal antibody
  Area: Immunology/Cancer/Tumor Marker
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Properties
- Host
  
  Mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  Human, Mouse, Rat
  
  Clone
  
  mAb
  
  Storage
  
  Long time storage is recommended at -20°C
  Phosphate-buffered solution, pH 7.2, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
  Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
  
  * For research use only.