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Overview
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Target Information
Target NameCd109 Antigen; 150 Kda Tgf-Beta-1-Binding Protein; C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 7; Platelet-Specific Gov Antigen; P180; R150; Cd Antigen Cd109Database LinksUniprot ID: MUSK_HUMAN ; Reactome: R-HSA-114608 ; Gene ID: 135228About TargetTissue Specificity: Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 4 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta.
Function: Modulates negatively TGFB1 signaling in keratinocytes.
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Overview