Human bisulfite modified genomic DNA controls including 15 ul of each low, medium, and high methylated DNAs

We offer methylated genomic DNA controls to serve as positive or negative controls in DNA methylation analysis experiments. The controls have been used on more than 14,000 gene-specific and global methylation assays using targeted bisulfite NGS (tNGBS), Pyrosequencing, and MS-HRM. They are recommended for use in DNA methylation assay development, optimization, and validation to ensure assay linearity, specificity, and reproducibility for research and clinical applications.

Our highly methylated DNA is in vitro enzymatically methylated genomic DNA with greater than 85% methylation. Our low methylated DNA is chemically and enzymatically treated with lower than 5% methylation. They are tested on numerous gene-specific and global methylation assays using pyrosequencing technology.

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