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Overview
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This ADIPOR2 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameAdiponectin Receptor Protein 2; Progestin And Adipoq Receptor Family Member 2; Progestin And Adipoq Receptor Family Member IiDatabase LinksUniprot ID: DKK4_HUMAN ; Reactome: R-HSA-163680 ; Gene ID: 79602About TargetTissue Specificity: Ubiquitous. Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
Function: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels.
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