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Overview
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This ACE CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameAngiotensin-Converting Enzyme; Ace; Dipeptidyl Carboxypeptidase I; Kininase Ii; Cd Antigen Cd143 Cleaved Into - Angiotensin-Converting Enzyme - Soluble FormDatabase LinksUniprot ID: DAG1_HUMAN ; Reactome: R-HSA-2022377 ; Gene ID: 1636About TargetTissue Specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
Function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
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Overview