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HSP70

HSP70

Catalog Number:

EUL1097616UBP

Mfr. No.:

K1300

Price:

$279

Size:

25 µg

Quantity:

Add to Cart:

- Overview
  - HSP70 a critical chaperone protein that has a high affinity for unfolded polypeptide chains. It binds extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In cooperation with other chaperones, Hsp70 stabilizes preexistent proteins against aggregation and mediates the folding of newly translated polypeptides in the cytosol as well as within organelles. Hsp70 and Hsp40 recruit some misfolded proteins to the ubiquitin E3 ligase CHIP for ubiquitination.
    
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- Properties
  - Protein Name
    
    HSPA1A; HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    70 kDa
    
    Sequence
    
    NCBI RefSeq: NM_005345
    
    * Research Use Only

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